Re-gearing in my experience is a very worthwhile modification since we live at high elevation. Going from 4.3 to 4.88s will be very noticeable daily driving, on the highway, and crawling off-road.
I have a Tundra with the 4.7 that I re-geared from 3.90 to 4.56. The difference from gearing is very drastic with 33.5" tires on it. I have a 5speed auto and vvti - so for me that gear ratio is good. I am sure your 100 is heavier and your 4 speed auto (and engine with less hp/tq) would benefit more from the 4.88s.
The transfer case underdrive gears should be a much cheaper option and I believe accomplish the same ratio change.
I have a Tundra with the 4.7 that I re-geared from 3.90 to 4.56. The difference from gearing is very drastic with 33.5" tires on it. I have a 5speed auto and vvti - so for me that gear ratio is good. I am sure your 100 is heavier and your 4 speed auto (and engine with less hp/tq) would benefit more from the 4.88s.
The transfer case underdrive gears should be a much cheaper option and I believe accomplish the same ratio change.